Research map: Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID
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Papers in this map
Long COVID: major findings, mechanisms and recommendations
· Hannah Davis · 2023 · 4329 citations · Cited by this paper
Leave No Data Behind: Exploring a new paradigm in oncology with foundation models and large language models
· 2026 · Related
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
· Alba Grifoni · 2020 · 4053 citations · Cited by this paper
Self-sufficient killing of malignant tumors by an engineered cancer-selective gene circuit
· 2026 · Related
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
· Yannick Simoni · 2018 · 1438 citations · Cited by this paper
Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination
· 2026 · Related
Multiple early factors anticipate post-acute COVID-19 sequelae
· Yapeng Su · 2022 · 1239 citations · Cited by this paper
Combine antibody-drug conjugate with cmLumiOpto for triple-negative breast cancer treatment
· 2026 · Related
Considering how biological sex impacts immune responses and COVID-19 outcomes
· Eileen P. Scully · 2020 · 1007 citations · Cited by this paper
Case of complete response to immunotherapy in MMR-deficient prostate cancer associated with NK-like and CD4+CD8+ T cells
· 2026 · Related
Distinguishing features of long COVID identified through immune profiling
· Jon Klein · 2023 · 723 citations · Cited by this paper
Therapeutic Gfral silencing via antisense oligonucleotides ameliorates cancer-associated cachexia and extends survival in tumor-bearing mice
· 2026 · Related
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases
· Alison Tarke · 2021 · 584 citations · Cited by this paper
Köhlmeier-Degos disease is an interferonopathy characterized by type I and II interferon-driven inflammatory vasculopathy
· 2026 · Related
Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency
· Yannick Simoni · 2016 · 437 citations · Cited by this paper
Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults
· 2026 · Related
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
· Carlo Cervia · 2024 · 415 citations · Cited by this paper
Alterations of the host-lung microbiome metasystem in systemic inflammatory response syndrome is associated with secondary pneumonia
· 2026 · Related
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
· Kailin Yin · 2024 · 369 citations · Cited by this paper
An autonomous multimodal AI agent for evidence-grounded ophthalmic diagnosis
· 2026 · Related
Long Covid Defined
· Eugene Wesley Ely · 2024 · 343 citations · Cited by this paper
Mechanisms of long COVID and the path toward therapeutics
· Michael J. Peluso · 2024 · 340 citations · Cited by this paper
Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization
· Evan William Newell · 2013 · 311 citations · Cited by this paper
Stronger inflammatory/cytotoxic T-cell response in women identified by microarray analysis
· Anura Hewagama · 2009 · 310 citations · Cited by this paper
Human CD4 + CD103 + cutaneous resident memory T cells are found in the circulation of healthy individuals
· Maria M. Klicznik · 2019 · 269 citations · Cited by this paper
SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8 + T cell activation in COVID-19 patients
· Sunil Kumar Saini · 2021 · 262 citations · Cited by this paper
Sestrins induce natural killer function in senescent-like CD8+ T cells
· Branca Isabel Pereira · 2020 · 249 citations · Cited by this paper
Chronic viral coinfections differentially affect the likelihood of developing long COVID
· Michael J. Peluso · 2022 · 229 citations · Cited by this paper
Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level
· Sven Hendrik Hagen · 2020 · 163 citations · Cited by this paper
Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy
· Jingwei Sun · 2020 · 149 citations · Cited by this paper
Normal haematological values: sex difference in neutrophil count.
· Barbara Jane Bain · 1975 · 148 citations · Cited by this paper
CD29 identifies IFN-γ–producing human CD8 + T cells with an increased cytotoxic potential
· Benoît P. Nicolet · 2020 · 127 citations · Cited by this paper
Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection
· Michael J. Peluso · 2024 · 108 citations · Cited by this paper
Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19
· Jason A. Neidleman · 2021 · 106 citations · Cited by this paper
Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement
· Michael J. Peluso · 2021 · 103 citations · Cited by this paper
Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation
· Eileen P. Scully · 2018 · 102 citations · Cited by this paper
TCF-1 regulates HIV-specific CD8+ T cell expansion capacity
· Rachel Lena Rutishauser · 2020 · 93 citations · Cited by this paper
Sex differences in tissue-specific immunity and immunology
· Sonia Sharma · 2025 · 76 citations · Cited by this paper
Targeting the SARS-CoV-2 reservoir in long COVID
· Amy D. Proal · 2025 · 63 citations · Cited by this paper
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