Research map: Engineered exosomes improve myocardial cell membrane integrity and heart function in dystrophic cardiomyopathy

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  1. The biology , function , and biomedical applications of exosomes · Raghu K. Kalluri · 2020 · 10967 citations · Cited by this paper
  2. Remodelling the tumour microenvironment and beyond: ERO1A as a multifaceted regulator and emerging therapeutic target in cancer · 2026 · Related
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  7. Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide · Adam C. Vandergriff · 2018 · 412 citations · Cited by this paper
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  9. Dystrophin-Deficient Cardiomyopathy · Forum D. Kamdar · 2016 · 395 citations · Cited by this paper
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  11. Therapeutic developments for Duchenne muscular dystrophy · Ingrid E.C. Verhaart · 2019 · 395 citations · Cited by this paper
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  13. Duchenne muscular dystrophy and dystrophin: pathogenesis and opportunities for treatment · Kristen J Nowak · 2004 · 366 citations · Cited by this paper
  14. Releasing the neuronal brake: Inhibiting AhR to enhance axon regeneration · 2026 · Related
  15. Life expectancy at birth in Duchenne muscular dystrophy: a systematic review and meta-analysis · Erik Landfeldt · 2020 · 303 citations · Cited by this paper
  16. The emerging dialogue between synthetic genomics and clinical research · 2026 · Related
  17. Effect of genetic background on the dystrophic phenotype in mdx mice · William Coley · 2015 · 264 citations · Cited by this paper
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  19. Extracellular vesicles: The next generation in gene therapy delivery · Riccardo Cecchin · 2023 · 201 citations · Cited by this paper
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  21. Identification of targeting peptides for ischemic myocardium by in vivo phage display · Sachiko Kanki · 2011 · 177 citations · Cited by this paper
  22. Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles · Eleni Tseliou · 2015 · 155 citations · Cited by this paper
  23. Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review · Zhen Chen · 2024 · 147 citations · Cited by this paper
  24. Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy · Ariel Bier · 2018 · 143 citations · Cited by this paper
  25. Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy · Mark A. Aminzadeh · 2018 · 142 citations · Cited by this paper
  26. Low dystrophin levels increase survival and improve muscle pathology and function in dystrophin/utrophin double‐knockout mice · Maaike van Putten · 2013 · 118 citations · Cited by this paper
  27. Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy · Courtney S. Young · 2017 · 102 citations · Cited by this paper
  28. Effects of exosome-mediated delivery of myostatin propeptide on functional recovery of mdx mice · Ning Ran · 2020 · 101 citations · Cited by this paper
  29. Mesenchymal stem cell-derived exosomes in cardiovascular and cerebrovascular diseases: From mechanisms to therapy · Yanhong Pan · 2023 · 90 citations · Cited by this paper
  30. Engineering exosomes and exosome-like nanovesicles for improving tissue targeting and retention · Lanya Li · 2024 · 79 citations · Cited by this paper
  31. Targeted Gene Delivery to Ischemic Myocardium by Homing Peptide-Guided Polymeric Carrier · Young-Wook Won · 2012 · 66 citations · Cited by this paper
  32. Cardiovascular Disease in Duchenne Muscular Dystrophy · Taylor Schultz · 2022 · 66 citations · Cited by this paper
  33. Inhalable cardiac targeting peptide modified nanomedicine prevents pressure overload heart failure in male mice · Haobo Weng · 2024 · 57 citations · Cited by this paper
  34. Associations between timing of corticosteroid treatment initiation and clinical outcomes in Duchenne muscular dystrophy · Sun Kyung Kim · 2017 · 51 citations · Cited by this paper
  35. Murine models of Duchenne muscular dystrophy: is there a best model? · Kristy Swiderski · 2021 · 49 citations · Cited by this paper
  36. Therapeutic Exon Skipping Through a CRISPR-Guided Cytidine Deaminase Rescues Dystrophic Cardiomyopathy in Vivo · Jia Li · 2021 · 49 citations · Cited by this paper
  37. Engineering M2 macrophage-derived exosomes modulate activated T cell cuproptosis to promote immune tolerance in rheumatoid arthritis · Guoquan Wu · 2024 · 42 citations · Cited by this paper
  38. CRISPR/Cas9-generated mouse model of Duchenne muscular dystrophy recapitulating a newly identified large 430 kb deletion in the human DMD gene · Tatiana V. Egorova · 2019 · 40 citations · Cited by this paper
  39. Exosome-mediated improvement in membrane integrity and muscle function in dystrophic mice · Ling Li Leng · 2020 · 37 citations · Cited by this paper

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