Research map: Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Back to the article

Papers in this map

  1. Empagliflozin in Heart Failure with a Preserved Ejection Fraction · Stefan D. Anker · 2021 · 4865 citations · Cited by this paper
  2. An Evaluation of Longitudinal Thyroid Hormone Levels Over the Years Before and After Patients Started on Levothyroxine · 2026 · Related
  3. Tirzepatide Once Weekly for the Treatment of Obesity · Ania M. Jastreboff · 2022 · 3661 citations · Cited by this paper
  4. The Effect of Integrated Lifestyle Intervention Incorporating Calorie‐Carbohydrate Restriction With or Without Time‐Restricted Feeding for Remission of Type 2 Diabetes ( DIREM ): A Single Blind Randomised Controlled Trial · 2026 · Related
  5. Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction · Scott David Solomon · 2022 · 2871 citations · Cited by this paper
  6. Frequency of Insulin Resistance in Overweight Patients With Metabolic‐Associated Fatty Liver Disease ( MAFLD ) at a Tertiary Healthcare Centre in Bangladesh · 2026 · Related
  7. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure · Paul A. Heidenreich · 2022 · 2815 citations · Cited by this paper
  8. Self‐Efficacy, Self‐Care, Glycaemic Control, and Quality of Life Among Adults With Type 2 Diabetes: A Scoping Review · 2026 · Related
  9. 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure · Theresa A. McDonagh · 2023 · 2438 citations · Cited by this paper
  10. Efficacy of Metformin in Prevention of Glucocorticoid‐Induced Hyperglycemia in Patients Without Diabetes: A Meta‐Analysis · 2026 · Related
  11. Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity · Mikhail Kosiborod · 2023 · 1621 citations · Cited by this paper
  12. A Clinically Aligned Two‐Stage Machine Learning Framework for Predicting Hungry Bone Syndrome After Parathyroidectomy · 2026 · Related
  13. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity · Milton Packer · 2024 · 950 citations · Cited by this paper
  14. Comparative Effectiveness of CagriSegma , Semaglutide, Cagrilintide and Tirzepatide in the Management of Overweight and Obesity: A Network Meta‐Analysis of Randomized Clinical Trials · 2026 · Related
  15. Tirzepatide for Metabolic Dysfunction–Associated Steatohepatitis with Liver Fibrosis · Rohit Seth Loomba · 2024 · 942 citations · Cited by this paper
  16. Predicting Diabetic Foot Ulcer Outcomes: Machine Learning‐Based Refinement of IWGDF ‐Approved Classifications for Outpatient Services · 2026 · Related
  17. Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. · Svetlana Mojsov · 1987 · 888 citations · Cited by this paper
  18. Reassessing Agreement Between Point of Care and Laboratory Triglyceride Measurements in High Risk Pregnancy · 2026 · Related
  19. Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes · Mikhail Kosiborod · 2024 · 722 citations · Cited by this paper
  20. Association of Selected Anthropometric Indices With Diabetic Kidney Disease Among Iranian Adults With Diabetes · 2026 · Related
  21. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes · Pantelis A. Sarafidis · 2016 · 711 citations · Cited by this paper
  22. Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF · Sanjiv Jayendra Shah · 2018 · 641 citations · Cited by this paper
  23. Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets · Barry A. Borlaug · 2022 · 444 citations · Cited by this paper
  24. Tirzepatide for Obesity Treatment and Diabetes Prevention · Ania M. Jastreboff · 2024 · 441 citations · Cited by this paper
  25. HF STATS 2024: Heart Failure Epidemiology and Outcomes Statistics An Updated 2024 Report from the Heart Failure Society of America · Biykem Bozkurt · 2024 · 424 citations · Cited by this paper
  26. Empagliflozin Increases Cardiac Energy Production in Diabetes · Subodh Verma · 2018 · 387 citations · Cited by this paper
  27. Empagliflozin Effects on Pulmonary Artery Pressure in Patients With Heart Failure · Michael E. Nassif · 2021 · 291 citations · Cited by this paper
  28. Mechanistic Insights of Empagliflozin in Nondiabetic Patients With HFrEF · Juan Antonio Requena-Ibáñez · 2021 · 272 citations · Cited by this paper
  29. Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics · Stephen James Nicholls · 2023 · 240 citations · Cited by this paper
  30. Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin · Rio P. Juni · 2019 · 207 citations · Cited by this paper
  31. Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure · Christopher M. Kramer · 2024 · 175 citations · Cited by this paper
  32. Lean Mass Abnormalities in Heart Failure: The Role of Sarcopenia, Sarcopenic Obesity, and Cachexia · Salvatore Carbone · 2019 · 171 citations · Cited by this paper
  33. Euglycemic diabetic ketoacidosis in the era of SGLT-2 inhibitors · Erica Chow · 2023 · 163 citations · Cited by this paper
  34. Body composition changes during weight reduction with tirzepatide in the SURMOUNT ‐1 study of adults with obesity or overweight · Michelle Look · 2025 · 146 citations · Cited by this paper
  35. Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial · Barry A. Borlaug · 2023 · 142 citations · Cited by this paper
  36. Efficacy and Safety of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction According to Age: The DELIVER Trial · Alexander Peikert · 2022 · 135 citations · Cited by this paper
  37. Emerging roles of SGLT2 inhibitors in obesity and insulin resistance: Focus on fat browning and macrophage polarization · Liang Xu · 2017 · 134 citations · Cited by this paper
  38. Connecting epicardial adipose tissue and heart failure with preserved ejection fraction: mechanisms, management and modern perspectives · Gijs van Woerden · 2022 · 124 citations · Cited by this paper
  39. Obesity, venous capacitance, and venous compliance in heart failure with preserved ejection fraction · Hidemi Sorimachi · 2021 · 123 citations · Cited by this paper

Source: OpenAlex (CC0)