Research map: Ferroptosis in multiple myeloma: molecular mechanisms and therapeutic opportunities

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  1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death · Scott J. Dixon · 2012 · 19067 citations · Cited by this paper
  2. Contrast-enhanced ultrasound-guided biopsy and perfusion monitoring for bladder involvement in relapsed multiple myeloma: a case report · 2026 · Related
  3. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease · Brent R. Stockwell · 2017 · 7879 citations · Cited by this paper
  4. Adaptive dosing of immunotherapy plus anti-angiogenic therapy in a nonagenarian with hepatocellular carcinoma: a case report with 10-year survival · 2026 · Related
  5. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition · Sebastian G. Doll · 2016 · 4318 citations · Cited by this paper
  6. Predictors and prevalence of lateral supraclavicular lymph node metastases on [18F]FDG PET/CT in patients with locally advanced, or multifocal invasive ductal carcinoma of breast: potential impact on adjuvant radiotherapy targets · 2026 · Related
  7. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis · Kirill Bersuker · 2019 · 3782 citations · Cited by this paper
  8. Case Report: a hypermetabolic mediastinal mass (SUVmax 16.7) mimicking malignancy with spontaneous resolution: an inflammatory myofibroblastic proliferation and diagnostic pitfall · 2026 · Related
  9. FSP1 is a glutathione-independent ferroptosis suppressor · Sebastian G. Doll · 2019 · 3412 citations · Cited by this paper
  10. Variations in histopathological and molecular subtypes between primary breast carcinoma and associated liver metastatic lesions · 2026 · Related
  11. Broadening horizons: the role of ferroptosis in cancer · Xin Chen · 2021 · 3014 citations · Cited by this paper
  12. Concurrent icotinib and definitive radiotherapy followed by detection of an EGFR exon 20 insertion at disease progression in unresectable stage III EGFR S768I-mutant lung adenocarcinoma: a case report · 2026 · Related
  13. Autophagy promotes ferroptosis by degradation of ferritin · Wen‐Chi Hou · 2016 · 2340 citations · Cited by this paper
  14. Perioperative outcomes and prognostic determinants in adult spindle cell/sclerosing rhabdomyosarcoma: implications of treatment intensity, surgical margins, and molecular heterogeneity · 2026 · Related
  15. Ferroptosis: machinery and regulation · Xin Chen · 2020 · 2132 citations · Cited by this paper
  16. The combined compartmental maxillary resection: technique codification and preliminary multicenter series analysis · 2026 · Related
  17. Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells · Jan Krönke · 2013 · 1904 citations · Cited by this paper
  18. Baseline 18F-FDG PET/CT metabolic parameters and systemic inflammatory markers in advanced NSCLC treated with first-line immunotherapy: an exploratory retrospective analysis · 2026 · Related
  19. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition · Matthew J. Hangauer · 2017 · 1840 citations · Cited by this paper
  20. Epigenetic and post-translational regulatory networks of ferroptosis in the tumor immune microenvironment · 2026 · Related
  21. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis · Irina Ingold · 2017 · 1696 citations · Cited by this paper
  22. RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels · Nicholas Yagoda · 2007 · 1657 citations · Cited by this paper
  23. GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling · Vanessa A. N. Kraft · 2019 · 1309 citations · Cited by this paper
  24. Identification of ACSL4 as a biomarker and contributor of ferroptosis · Hua Yuan · 2016 · 1092 citations · Cited by this paper
  25. Diagnosis and Management of Multiple Myeloma · Andrew J. Cowan · 2022 · 1038 citations · Cited by this paper
  26. Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies · Qian Zhou · 2024 · 869 citations · Cited by this paper
  27. Ferroptosis in infection, inflammation, and immunity · Xin Chen · 2021 · 833 citations · Cited by this paper
  28. The interaction between ferroptosis and lipid metabolism in cancer · Dingshan Li · 2020 · 731 citations · Cited by this paper
  29. Genomic complexity of multiple myeloma and its clinical implications · Salomon Manier · 2016 · 579 citations · Cited by this paper
  30. Regulation of ferroptosis by lipid metabolism · Lauren E. Pope · 2023 · 575 citations · Cited by this paper
  31. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity · Chengxian Xu · 2021 · 525 citations · Cited by this paper
  32. Clockophagy is a novel selective autophagy process favoring ferroptosis · Minghua Yang · 2019 · 498 citations · Cited by this paper
  33. Multiple myeloma: 2024 update on diagnosis, risk‐stratification, and management · S. Vincent Rajkumar · 2024 · 496 citations · Cited by this paper
  34. Bone Marrow Microenvironment in Multiple Myeloma Progression · Salomon Manier · 2012 · 297 citations · Cited by this paper
  35. GPX4-independent ferroptosis—a new strategy in disease’s therapy · Tianyu Ma · 2022 · 268 citations · Cited by this paper
  36. The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape · Madelon M.E. de Jong · 2021 · 250 citations · Cited by this paper
  37. Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug · Jinsong Hu · 2010 · 159 citations · Cited by this paper
  38. The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma · Sally K. Martin · 2011 · 127 citations · Cited by this paper
  39. Mechanisms and regulations of ferroptosis · Xu-Dong Zhang · 2023 · 124 citations · Cited by this paper

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