Research map: Jiajian Shuyu Pills ameliorates cerebral ischemia-reperfusion injury by regulation hippo signaling and the lipid metabolism-ferroptosis axis

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  1. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis · Valerian E. Kagan · 2016 · 3004 citations · Cited by this paper
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  11. Quercetin attenuates cerebral ischemic injury by inhibiting ferroptosis via Nrf2/HO-1 signaling pathway · Caiwang Peng · 2023 · 86 citations · Cited by this paper
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  18. Yishen Tongluo formula regulates apoptosis and autophagy in testicular spermatogenic cells of oligoasthenozoospermic rats via the AMPK/mTOR pathway · 2026 · Related
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  22. Dynamic Brain Lipid Profiles Modulate Microglial Lipid Droplet Accumulation and Inflammation Under Ischemic Conditions in Mice · Wei Wei · 2024 · 55 citations · Cited by this paper
  23. Network pharmacology provides new insights into the mechanism of traditional Chinese medicine and natural products used to treat pulmonary hypertension · Xinyue Wang · 2024 · 54 citations · Cited by this paper
  24. Quercetin alleviates metabolic-associated fatty liver disease by tuning hepatic lipid metabolism, oxidative stress and inflammation · Ling Jiang · 2024 · 51 citations · Cited by this paper
  25. Single-cell RNA sequencing unveils Lrg1's role in cerebral ischemia‒reperfusion injury by modulating various cells · Zhaohui Ruan · 2023 · 47 citations · Cited by this paper
  26. Network Pharmacology-Driven Sustainability: AI and Multi-Omics Synergy for Drug Discovery in Traditional Chinese Medicine · Lifang Yang · 2025 · 47 citations · Cited by this paper
  27. Single-cell transcriptomic profiling of heart reveals ANGPTL4 linking fibroblasts and angiogenesis in heart failure with preserved ejection fraction · Guoxing Li · 2024 · 43 citations · Cited by this paper
  28. Developing targeted antioxidant nanomedicines for ischemic penumbra: Novel strategies in treating brain ischemia-reperfusion injury · Zhitao Hou · 2024 · 43 citations · Cited by this paper
  29. Hypoxanthine is a metabolic biomarker for inducing GSDME-dependent pyroptosis of endothelial cells during ischemic stroke · Jing Ye · 2024 · 42 citations · Cited by this paper
  30. Role of lipids in interorganelle communication · Neuza S. Domingues · 2024 · 39 citations · Cited by this paper
  31. Polygala tenuifolia willd. Extract alleviates LPS-induced acute lung injury in rats via TLR4/NF-κB pathway and NLRP3 inflammasome suppression · Shuyun Guo · 2024 · 39 citations · Cited by this paper
  32. An update on the role of Hippo signaling pathway in ischemia-associated central nervous system diseases · Xuan Wei · 2023 · 37 citations · Cited by this paper
  33. Multi-omics approaches for the understanding of therapeutic mechanism for Huang-Qi-Long-Dan Granule against ischemic stroke · Chuanhong Wu · 2024 · 35 citations · Cited by this paper
  34. Application of network pharmacology in synergistic action of Chinese herbal compounds · Xianchun Duan · 2024 · 35 citations · Cited by this paper
  35. Pathophysiology of cerebral ischemia-reperfusion injury: An overview of oxidative stress and plant-based therapeutic approaches · Wasim Akhtar · 2024 · 27 citations · Cited by this paper
  36. Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability · Xiaoling Zhang · 2024 · 22 citations · Cited by this paper
  37. An update on the role of ferroptosis in ischemic stroke: from molecular pathways to Neuroprotection · A Gowtham · 2024 · 21 citations · Cited by this paper
  38. Integrative microbiomics, proteomics and lipidomics studies unraveled the preventive mechanism of Shouhui Tongbian Capsules on cerebral ischemic stroke injury · Fangjiao Wei · 2024 · 20 citations · Cited by this paper
  39. Danhong injection improves neurological function in rats with ischemic stroke by enhancing neurogenesis and activating BDNF/AKT/CREB signaling pathway · Lan Li · 2023 · 19 citations · Cited by this paper

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