Research map: Rethinking lymphodepleting preconditioning in adoptive T cell therapy for durable tumor control
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Papers in this map
Adoptive cell transfer as personalized immunotherapy for human cancer
· Steven A. Rosenberg · 2015 · 2547 citations · Cited by this paper
CAR design equips diverse immune cells with unique antigen-specific activation identities
· Ayano Sugiyama-Finnis · 2026 · Related
Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma
· Mark E. Dudley · 2005 · 1641 citations · Cited by this paper
Depletion of IL-10 in CAR-NK cells augments reprogramming of the tumor microenvironment and ameliorates therapeutic efficacy
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Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy
· Stefani Spranger · 2017 · 1470 citations · Cited by this paper
AGTR1 signaling contributes to tumor immunity and therapy response in non-small cell lung cancer
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Tumor Antigen Escape from CAR T-cell Therapy
· Robbie G. Majzner · 2018 · 1213 citations · Cited by this paper
CART-immune-related adverse events after BCMA CAR-T therapy
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
· Martin Lauss · 2017 · 511 citations · Cited by this paper
Unmasking Wnt-driven HCC: Inhibiting SMYD2 to overcome immune resistance
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Cellular networks controlling T cell persistence in adoptive cell therapy
· Jack D. Chan · 2021 · 247 citations · Cited by this paper
Intraperitoneal delivery of the oncolytic virus CF17 improves tumor immunogenicity and survival in gastric cancer peritoneal metastasis
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Endogenous T cells prevent tumor immune escape following adoptive T cell therapy
· Scott R. Walsh · 2019 · 111 citations · Cited by this paper
Synergistic Cell-Cycle Repression by HDAC/EZH2 Co-Targeting in H3K27-Altered Diffuse Midline Glioma
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Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8 + T-myeloid cell networks in melanoma
· David Barras · 2024 · 97 citations · Cited by this paper
Natural killer cell-derived extracellular vesicles reprogram cellular human immunity to enhance tumor cytotoxicity
· 2026 · Related
Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse
· Luca Gattinoni · 2026 · 11 citations · Cited by this paper
Optimizing CAR T cell therapy in pancreatic cancer through clinically actionable combinations
· 2026 · Related
Lymphodepleting preconditioning impairs host antitumor immunity induced by adoptive T cell therapy in mouse models
· Diego A. Figueroa · 2026 · 2 citations · Cited by this paper
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