Research map: Pretreatment With BTK Inhibitors Improved the Sensitivity of DLBCL Cells to CAR ‐T Cells in a Coculture System by Downregulating the Polarisation of M2 Macrophages

Back to the article

Papers in this map

  1. Integrated analysis of multimodal single-cell data · Yuhan Hao · 2021 · 16919 citations · Cited by this paper
  2. GGAs : Regulation of Multiple Sorting Pathways and Potential Association With Human Diseases · 2026 · Related
  3. Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma · Sattva Swarup Neelapu · 2017 · 6103 citations · Cited by this paper
  4. Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways · 2026 · Related
  5. Tumour-associated macrophages as treatment targets in oncology · Alberto Mantovani · 2017 · 4192 citations · Cited by this paper
  6. Superoxide Dismutase–Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications · 2026 · Related
  7. Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma · Stephen J. Schuster · 2018 · 4159 citations · Cited by this paper
  8. PGK1 Drives Glial Glycolytic Reprogramming to Mediate Isoflurane‐Induced Cognitive Impairment in Aged Mice · 2026 · Related
  9. The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism · Raphael Kopan · 2009 · 3735 citations · Cited by this paper
  10. FTO ‐Catalysed Demethylation of LUR1 mRNA Suppresses Macrophage Lipid Accumulation and Aortic Atherosclerosis · 2026 · Related
  11. Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages · Marco Orecchioni · 2019 · 2142 citations · Cited by this paper
  12. HDAC2 ‐Mediated SMAD7 Stabilisation Activates Wnt/β‐Catenin Signalling to Drive DNA Damage Repair and Cisplatin Resistance in Ovarian Cancer · 2026 · Related
  13. Macrophages and Metabolism in the Tumor Microenvironment · Ilio Vitale · 2019 · 1933 citations · Cited by this paper
  14. The STAT3‐CCND2 Axis Drives a Proliferative Metaplastic Precursor Population in Gastric Intestinal Metaplasia · 2026 · Related
  15. Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor–Modified T Cells After Failure of Ibrutinib · Cameron John Turtle · 2017 · 669 citations · Cited by this paper
  16. Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury · 2026 · Related
  17. Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses · Yaochun Wang · 2010 · 482 citations · Cited by this paper
  18. circFOXP1 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Regulating EREG / MAPK / ERK Axis · 2026 · Related
  19. Five-Year Outcomes for Refractory B-Cell Lymphomas with CAR T-Cell Therapy · Elise A. Chong · 2021 · 343 citations · Cited by this paper
  20. KATP Channel Expression Determines ONC212 Sensitivity via Mitochondrial Dysfunction and PERK / ATF4 / CHOP Activation in Glioblastoma · 2026 · Related
  21. Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia · Ferran Nadeu · 2016 · 340 citations · Cited by this paper
  22. Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy · Kathryn M. Cappell · 2020 · 317 citations · Cited by this paper
  23. Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures · Nikita Kotlov · 2021 · 267 citations · Cited by this paper
  24. CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis · Yao‐Hui Huang · 2021 · 241 citations · Cited by this paper
  25. Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma · Nathalie Scholler · 2022 · 210 citations · Cited by this paper
  26. Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization · Weijuan Zhang · 2010 · 184 citations · Cited by this paper
  27. Functions of Notch Signaling in the Immune System: Consensus and Controversies · Julie S. Yuan · 2010 · 181 citations · Cited by this paper
  28. Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders · Daiju Fukuda · 2012 · 175 citations · Cited by this paper
  29. Anti-CD19 CAR T cells in combination with ibrutinib for the treatment of chronic lymphocytic leukemia · Saar I. Gill · 2022 · 133 citations · Cited by this paper
  30. Bruton's Tyrosine Kinase: From X-Linked Agammaglobulinemia Toward Targeted Therapy for B-Cell Malignancies · Sabine Ponader · 2014 · 125 citations · Cited by this paper
  31. Promoting antibody-dependent cellular phagocytosis for effective macrophage-based cancer immunotherapy · Xu Cao · 2022 · 116 citations · Cited by this paper
  32. Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia · Francesca Arruga · 2013 · 113 citations · Cited by this paper
  33. Notch signaling is necessary but not sufficient for differentiation of dendritic cells · Pingyan Cheng · 2003 · 87 citations · Cited by this paper
  34. Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands · Pingyan Cheng · 2006 · 86 citations · Cited by this paper
  35. The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection · Luca Arcaini · 2014 · 83 citations · Cited by this paper
  36. Ibrutinib for improved chimeric antigen receptor T‐cell production for chronic lymphocytic leukemia patients · Fuli Fan · 2020 · 80 citations · Cited by this paper
  37. Influence of oncogenic mutations and tumor microenvironment alterations on extranodal invasion in diffuse large B‐cell lymphoma · Rong Shen · 2020 · 80 citations · Cited by this paper
  38. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms · Kei Sakamoto · 2012 · 78 citations · Cited by this paper
  39. Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes · Xiao Zhang · 2015 · 77 citations · Cited by this paper

Source: OpenAlex (CC0)