Research map: From architecture to function: mechanisms shaping pancreatic islet morphogenesis

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  1. Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen · A.M. James Shapiro · 2000 · 5299 citations · Cited by this paper
  2. Spatial and functional mapping of the human pancreas reveals endocrine and exocrine cell states in health and metabolic disease · Yike Xie · 2026 · Cites this paper
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  10. Rfx6 directs islet formation and insulin production in mice and humans · Stuart B. Smith · 2010 · 372 citations · Cited by this paper
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  16. Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient · Shusen Wang · 2024 · 277 citations · Cited by this paper
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  18. Mechanosignalling via integrins directs fate decisions of pancreatic progenitors · Anant Mamidi · 2018 · 247 citations · Cited by this paper
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  20. Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse · David O. Morgan · 1998 · 242 citations · Cited by this paper
  21. Determinants and dynamics of pancreatic islet architecture · 2022 · Related
  22. Heterogeneous Requirement of NGF for Sympathetic Target InnervationIn Vivo · Natalia O. Glebova · 2004 · 235 citations · Cited by this paper
  23. Extra-insular beta cells associated with ductules are frequent in adult human pancreas · Luc Bouwens · 1998 · 228 citations · Cited by this paper
  24. Endocrine Cell Clustering During Human Pancreas Development · Jongmin Jeon · 2009 · 207 citations · Cited by this paper
  25. Sympathetic Innervation during Development Is Necessary for Pancreatic Islet Architecture and Functional Maturation · Philip M. Borden · 2013 · 195 citations · Cited by this paper
  26. Cellular and molecular mechanisms coordinating pancreas development · Aimée Bastidas-Ponce · 2017 · 184 citations · Cited by this paper
  27. Impact of islet architecture on β-cell heterogeneity, plasticity and function · Sara S. Roscioni · 2016 · 183 citations · Cited by this paper
  28. Neural Cell Adhesion Molecule (N-CAM) Is Required for Cell Type Segregation and Normal Ultrastructure in Pancreatic Islets · Farzad Esni · 1999 · 175 citations · Cited by this paper
  29. Fat Aussie—A New Alstrom Syndrome Mouse Showing a Critical Role for ALMS1 in Obesity, Diabetes, and Spermatogenesis · Todor Arsov · 2006 · 172 citations · Cited by this paper
  30. Weaning Triggers a Maturation Step of Pancreatic β Cells · Miri Stolovich-Rain · 2015 · 161 citations · Cited by this paper
  31. Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development · M Gouzi · 2011 · 154 citations · Cited by this paper
  32. The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth · Yan Hang · 2014 · 147 citations · Cited by this paper
  33. Single-cell transcriptomic and spatial landscapes of the developing human pancreas · Oladapo Edward Olaniru · 2022 · 147 citations · Cited by this paper
  34. A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets · Nadav Sharon · 2019 · 130 citations · Cited by this paper
  35. Signals from the neural crest regulate beta-cell mass in the pancreas · Nada Nekrep · 2008 · 117 citations · Cited by this paper
  36. Paracrine regulation of insulin secretion · Mark O. Huising · 2020 · 112 citations · Cited by this paper
  37. Primary cilia control glucose homeostasis via islet paracrine interactions · Jing W. Hughes · 2020 · 104 citations · Cited by this paper
  38. Novel Function of the Ciliogenic Transcription Factor RFX3 in Development of the Endocrine Pancreas · Aouatef Ait‐Lounis · 2007 · 102 citations · Cited by this paper
  39. Modelling the endocrine pancreas in health and disease · Mostafa Bakhti · 2018 · 101 citations · Cited by this paper

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