Research map: Application of the Allen Human Brain Atlas in Alzheimer’s disease and Parkinson’s disease

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Papers in this map

  1. An anatomically comprehensive atlas of the adult human brain transcriptome · Michael Hawrylycz · 2012 · 3410 citations · Cited by this paper
  2. Age-dependent removal of Atg9-containing vesicle accumulations in motoneuron disease models by physical exercise · 2025 · Related
  3. Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse · Ye Zhang · 2015 · 2540 citations · Cited by this paper
  4. Reduced synaptic vesicle protein 2A in extracellular vesicles and brains of Alzheimer’s disease: associations with Aβ, tau, synaptic proteins and APOE ε4 · 2025 · Related
  5. Spatio-temporal transcriptome of the human brain · Hyo Jung Kang · 2011 · 2231 citations · Cited by this paper
  6. Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease · 2025 · Related
  7. A survey of human brain transcriptome diversity at the single cell level · Spyros Darmanis · 2015 · 1604 citations · Cited by this paper
  8. Attenuating α-synuclein pathology in mice with in situ engineered astrocytes · 2025 · Related
  9. Massively parallel single-nucleus RNA-seq with DroNc-seq · Naomi Habib · 2017 · 1223 citations · Cited by this paper
  10. Stratification of brain-derived extracellular vesicles of Alzheimer’s disease patients indicates a unique proteomic content and a higher seeding capacity of small extracellular vesicles · 2025 · Related
  11. Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain · Blue B. Lake · 2017 · 1107 citations · Cited by this paper
  12. LRRK2 G2019S mutation contributes to mitochondrial transfer dysfunction in a Drp1-STX17-dependent manner · 2025 · Related
  13. Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram · Tommaso Biancalani · 2021 · 980 citations · Cited by this paper
  14. Proximity labeling in neuroscience: decoding molecular landscapes for precision neurology · 2026 · Related
  15. A practical guide to linking brain-wide gene expression and neuroimaging data · Aurina Arnatkevičiūtė · 2019 · 920 citations · Cited by this paper
  16. Microbiota and Alzheimer’s disease: mechanistic insights from a multi-organ perspective · 2026 · Related
  17. Integrative functional genomic analysis of human brain development and neuropsychiatric risks · Mingfeng Li · 2018 · 907 citations · Cited by this paper
  18. Lysophagy protects against ANXA11 amyloid fibril toxicity and propagation in FTLD · 2026 · Related
  19. On testing for spatial correspondence between maps of human brain structure and function · Aaron F. Alexander‐Bloch · 2018 · 902 citations · Cited by this paper
  20. The Drp1-CoQ10-Coa6-ETC axis represents a therapeutic potential for working memory impairment caused by neuronal mitochondrial dysfunction · 2026 · Related
  21. Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases · Jing Guo · 2014 · 667 citations · Cited by this paper
  22. Standardizing workflows in imaging transcriptomics with the abagen toolbox · Ross D Markello · 2021 · 554 citations · Cited by this paper
  23. Molecularly defined and spatially resolved cell atlas of the whole mouse brain · Meng Zhang · 2023 · 519 citations · Cited by this paper
  24. Bridging the Gap between Connectome and Transcriptome · Alex Fornito · 2018 · 449 citations · Cited by this paper
  25. Comparing spatial null models for brain maps · Ross D. Markello · 2021 · 392 citations · Cited by this paper
  26. Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease · Gargi Ganguly · 2017 · 290 citations · Cited by this paper
  27. Staging β -Amyloid Pathology With Amyloid Positron Emission Tomography · Niklas Mattsson · 2019 · 247 citations · Cited by this paper
  28. Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer’s Disease · Roger J. Mullins · 2017 · 219 citations · Cited by this paper
  29. Neurogenetic contributions to amyloid beta and tau spreading in the human cortex · Jorge Sepulcre · 2018 · 212 citations · Cited by this paper
  30. Global, regional, and national burden of neurological disorders in 204 countries and territories worldwide · Yi Huang · 2023 · 196 citations · Cited by this paper
  31. Compilation of reported protein changes in the brain in Alzheimer’s disease · Manor Askenazi · 2023 · 190 citations · Cited by this paper
  32. Revised criteria for the diagnosis and staging of Alzheimer’s disease · Clifford R. Jack · 2024 · 188 citations · Cited by this paper
  33. Cerebral Iron Deposition in Neurodegeneration · Petr Dušek · 2022 · 162 citations · Cited by this paper
  34. Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways · Aleksandra Wojtas · 2017 · 160 citations · Cited by this paper
  35. Exosomal biomarkers of brain insulin resistance associated with regional atrophy in Alzheimer's disease · Roger J. Mullins · 2017 · 130 citations · Cited by this paper
  36. Brain Metabolic Alterations in Alzheimer’s Disease · Carlos G. Ardanaz · 2022 · 127 citations · Cited by this paper
  37. Toward Best Practices for Imaging Transcriptomics of the Human Brain · Aurina Arnatkevičiūtė · 2022 · 121 citations · Cited by this paper
  38. Regional brain iron and gene expression provide insights into neurodegeneration in Parkinson’s disease · George E. C. Thomas · 2021 · 119 citations · Cited by this paper
  39. Imaging Transcriptomics of Brain Disorders · Aurina Arnatkevičiūtė · 2021 · 110 citations · Cited by this paper

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