Research map: Long-term exercise enhances meningeal lymphatic vessel plasticity and drainage in a mouse model of Alzheimer's disease

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  1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics · John Hardy · 2002 · 14018 citations · Cited by this paper
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  12. Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease · 2025 · Related
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  16. The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease · Michael W. Gleeson · 2011 · 2481 citations · Cited by this paper
  17. The therapeutic potential of early exercise in Alzheimer's disease: Focus on the brain-spleen axis · Tao Wang · 2025 · 4 citations · Cites this paper
  18. Stratification of brain-derived extracellular vesicles of Alzheimer’s disease patients indicates a unique proteomic content and a higher seeding capacity of small extracellular vesicles · 2025 · Related
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  20. Running exercise mitigates amyloidosis in 5xFAD mice by improving the structure and function of the meningeal lymphatic system · Onanong Mee-inta · 2026 · 3 citations · Cites this paper
  21. Alzheimer's disease · Colin Louis Masters · 2015 · 1824 citations · Cited by this paper
  22. The glymphatic system as a brain scavenger in Alzheimer’s disease: mechanisms and therapeutic implications · Manyv Zheng · 2026 · 3 citations · Cites this paper
  23. Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease · Sandro Dá Mesquita · 2018 · 1486 citations · Cited by this paper
  24. Neuroprotective cellular and molecular mechanisms of physical exercise on neurodegenerative diseases · S.K. Sahoo · 2026 · 1 citation · Cites this paper
  25. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline · Tyler J. Bussian · 2018 · 1321 citations · Cited by this paper
  26. Bypass the Brain: Deep Cervical Lymphatic-Venous Anastomosis Restores the Default Mode Network in Late-stage Alzheimer's Disease · Haishuo Xia · 2025 · 1 citation · Cites this paper
  27. CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior · Roy L. Silverstein · 2009 · 1281 citations · Cited by this paper
  28. Research progress on vascular endothelial growth factor C in meningeal lymphatic vessel-mediated clearance of amyloid β-protein · Zhaoxie YU · 2026 · Cites this paper
  29. Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model · Se Hoon Choi · 2018 · 841 citations · Cited by this paper
  30. Meningeal lymphatic dysfunction in Alzheimer’s disease: molecular mechanisms, clinical implications, and future perspectives · lian Liu · 2026 · Cites this paper
  31. Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid · Ji Hoon Ahn · 2019 · 829 citations · Cited by this paper
  32. Serial failure of the brain clearance continuum in Alzheimer’s disease: mechanisms and therapeutic perspectives · Qi Yao · 2026 · Cites this paper
  33. The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future · Benjamin A. Plog · 2017 · 808 citations · Cited by this paper
  34. Bypass the Brain: Deep Cervical Lymphatic-Venous Anastomosis Restores the Default Mode Network in Late-stage Alzheimer's Disease · Haishuo Xia · 2025 · Cites this paper
  35. Fluid transport in the brain · Martin Kaag Rasmussen · 2021 · 620 citations · Cited by this paper
  36. Physical activity and the brain barriers: Mechanisms of neuroprotection and disease resilience · Julia Morys · 2026 · Cites this paper
  37. Development and plasticity of meningeal lymphatic vessels · Salli Antila · 2017 · 491 citations · Cited by this paper
  38. Exercise as a regulator of glymphatic function · James R. Broatch · 2026 · Cites this paper
  39. Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy · Sandro Dá Mesquita · 2021 · 438 citations · Cited by this paper

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