Defining and interpreting the clinical relevance of intervention effects for patient-reported outcomes: the smallest worthwhile effect construct

BMJ Evidence-Based Medicine · Published 2026-07-23 · DOI 10.1136/bmjebm-2026-114620

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Authors (11)

Tiziano Innocenti, Tim Schleimer, Maarten de Wit, Manuela Ferreira, Toshi A Furukawa, Harrison J Hansford, James H McAuley, Georgia Salanti, Stefano Salvioli, Raymond Ostelo, Alessandro Chiarotto

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Year

2026

Citation

Innocenti, T., Schleimer, T., Wit, M., et al. (2026). Defining and interpreting the clinical relevance of intervention effects for patient-reported outcomes: the smallest worthwhile effect construct. BMJ Evidence-Based Medicine. https://doi.org/10.1136/bmjebm-2026-114620

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