Molecular Cytogenetics · Published 2026-06-19 · DOI 10.1186/s13039-026-00767-2
Maliha Naz, Jawad Hassan, Neelum Mansoor
Abstract t(14;15) have rarely been seen in hematologic malignancies. Here we have reported a case of a 4-year-old male who presented with low grade fever and body aches and, was diagnosed on immunophenotyping as B-cell Acute Lymphoblastic Leukemia. Cytogenetic analysis demonstrated a previously unreported translocation t(14;15)(q32;q11.2). Fluorescent in situ hybridization (FISH) analysis on metaphases was also carried out to confirm the chromosomal aberration. To our knowledge, such a translocation has not been reported in hematological malignancy specifically in B-cell ALL.
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Naz, M., Hassan, J., Mansoor, N. (2026). Previously unreported translocation (14;15)(q32; q11.2) observed in B-cell acute lymphoblastic leukemia: a case report. Molecular Cytogenetics. https://doi.org/10.1186/s13039-026-00767-2