Clinical and Experimental Hypertension · Published 2026-08-03 · DOI 10.1080/10641963.2026.2712543
Yuanyuan Shi, Pengjie Gao, Xingyue Lin, Molei Zhang, Danni Wang, Kamila Kamili, Xiyang Li, Suining Xu, Gang Tian
This cross-sectional study aimed to analyze whether inter-ankle systolic blood pressure difference (sIAND) was associated with different stages of hypertensive renal damage. 1,658 and 831 nondiabetic hypertensive patients were included from two cohorts. The hypertensive renal damage was reflected by urinary albumin-to-creatinine ratio (UACR), Cystatin C, and estimated glomerular filtration rate. Logistic regression results showed that sIAND was only associated with subclinical hypertensive renal damage reflected by microalbuminuria (UACR > 30 mg/g) independently. Receiver operating characteristic curves indicated sIAND can identify microalbuminuria more effectively. sIAND can aid in identifying microalbuminuria to provide useful clues for risk stratification and clinical management.
Abstract from DOAJ. Public domain (CC0 1.0).
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Shi, Y., Gao, P., Lin, X., et al. (2026). Inter-ankle systolic blood pressure difference is associated with microalbuminuria in non-diabetic hypertension patients: A cross-sectional study from two cohorts. Clinical and Experimental Hypertension. https://doi.org/10.1080/10641963.2026.2712543