Hormonal aspects of overtraining syndrome: a systematic review

BMC Sports Science, Medicine and Rehabilitation · Published 2017-12-01 · Available online 2 Aug 2017 · Journal article · DOI 10.1186/s13102-017-0079-8 · Cited by 119 (Crossref)

Authors (2)

Flavio A. Cadegiani, Claudio E. Kater

Abstract

Abstract Background Overtraining syndrome (OTS), functional (FOR) and non-functional overreaching (NFOR) are conditions diagnosed in athletes with decreased performance and fatigue, triggered by metabolic, immune, hormonal and other dysfunctions and resulted from an imbalance between training stress and proper recovery. Despite previous descriptions, there is a lack of a review that discloses all hormonal findings in OTS/FOR/NFOR. The aim of this systematic review is to evaluate whether and which roles hormones play in OTS/FOR/NFOR. Methods A systematic search up to June 15th, 2017 was performed in the PUBMED, MEDLINE and Cochrane databases following PRISMA protocol, with the expressions: (1)overtraining, (2)overreaching, (3)overtrained, (4)overreached, or (5)underperformance, and (plus) (a)hormone, (b)hormonal, (c)endocrine, (d)adrenal, (e)cortisol, (f)GH, (g)ACTH, (h)testosterone, (i)IGF-1, (j)TSH, (k)T4, (l)T3, (m)LH, (n)FSH, (o)prolactin, (p) IGFBP-3 and related articles. Results A total of 38 studies were selected. Basal levels of hormones were mostly normal in athletes with OTS/FOR/NFOR compared with healthy athletes. Distinctly, stimulation tests, mainly performed in maximal exercise conditions, showed blunted GH and ACTH responses in OTS/FOR/NFOR athletes, whereas cortisol and plasma catecholamines showed conflicting findings and the other hormones responded normally. Conclusion Basal hormone levels are not good predictor but blunted ACTH and GH responses to stimulation tests may be good predictors of OTS/FOR/NFOR.

Abstract from DOAJ. Public domain (CC0 1.0).

Read the article at the publisher →

Publication details

Volume
9
Issue
1
Year
2017

Citation

Cadegiani, F., Kater, C. (2017). Hormonal aspects of overtraining syndrome: a systematic review. BMC Sports Science, Medicine and Rehabilitation. https://doi.org/10.1186/s13102-017-0079-8

Related articles

Metrics

Citations (Crossref)
119