Rapamycin‐nanoliposomes target the mTORC1 ‐mediated autophagy–lysosomal and NLRP3 /Caspase‐1 pathways to inhibit nucleus pulposus cell senescence in intervertebral discs

Bioengineering & Translational Medicine · Published 2026-08-03 · DOI 10.1002/btm2.70165

Free full text

Authors (14)

Hui Xing, Miao Yu, Jiabin Liu, Runzhi Zhao, Xuezheng Ai, Rong Tang, Tong Zhu, Yuqing Li, Lu Jiang, Quanfang Wei, Youying Huang, Yu Guo, Tao Jiang, Bo Huang

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Xing, H., Yu, M., Liu, J., et al. (2026). Rapamycin‐nanoliposomes target the mTORC1 ‐mediated autophagy–lysosomal and NLRP3 /Caspase‐1 pathways to inhibit nucleus pulposus cell senescence in intervertebral discs. Bioengineering & Translational Medicine. https://doi.org/10.1002/btm2.70165

Related articles

• Stealth polymer coatings of reactive oxygen species scavenging nanoparticles for immune response mitigation · Bioengineering & Translational Medicine · 2026 · Same journal
• Stability of bacteriophages in spray‐dried polymeric formulations: Effect of excipient polyvinylpyrrolidone glass transition temperature and molecular weight · Bioengineering & Translational Medicine · 2026 · Same journal
• Evaluation of a functionalized chitosan and alginate multilayer conformal nanocoating toward improving islet survival in syngeneic mouse islet transplantation · Bioengineering & Translational Medicine · 2026 · Same journal
• PEGylated thymosin β4 is a thiol‐site‐specific prodrug treating myocardial infarction in vivo · Bioengineering & Translational Medicine · 2026 · Same journal
• Exogenous matrix‐free biomanufacturing of glioblastoma organoids enables autonomous assembly of neurovascular‐like structures and extracellular matrix · Bioengineering & Translational Medicine · 2026 · Same journal
• Mechanical fingerprints in breast cancer research: A multimodal experimental approach · Bioengineering & Translational Medicine · 2026 · Same journal
• Human induced pluripotent stem cell‐derived mesenchymal stromal cells regenerate diabetic ischemic muscle · Bioengineering & Translational Medicine · 2026 · Same journal
• Dynamic pillar–perfusion platform for screening enzyme‐induced self‐assembling peptide therapeutics in 3D breast cancer spheroids · Bioengineering & Translational Medicine · 2026 · Same journal
• Chimeric antigen receptor‐macrophages: A new paradigm for cell therapy · Bioengineering & Translational Medicine · 2026 · Same journal
• Physiological and functional characterization for high‐throughput optogenetic skeletal muscle exercise assays · Bioengineering & Translational Medicine · 2025 · Same journal