Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses

The Journal of Clinical Investigation · Published 2021-04-15 · Journal article · DOI 10.1172/jci140752 · Cited by 59 (Crossref)

Authors (33)

Fan Huang, Christophe Gonçalves, Margarita Bartish, Joelle Rémy-Sarrazin, Mark E. Issa, Brendan Cordeiro, Qianyu Guo, Audrey Emond, Mikhael Attias, William Yang, Dany Plourde, Jie Su, Marina Godoy Gimeno, Yao Zhan, Alba Galán, Tomasz Rzymski, Milena Mazan, Magdalena Masiejczyk, Jacek Faber, Elie Khoury, Alexandre Benoit, Natascha Gagnon, David Dankort, Fabrice Journe, Ghanem E. Ghanem, Connie M. Krawczyk, H. Uri Saragovi, Ciriaco A. Piccirillo, Nahum Sonenberg, Ivan Topisirovic, Christopher E. Rudd, Wilson H. Miller, Sonia V. del Rincón

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Volume

131

Issue

8

Year

2021

Citation

Huang, F., Gonçalves, C., Bartish, M., et al. (2021). Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses. The Journal of Clinical Investigation. https://doi.org/10.1172/jci140752

Related articles

• Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle · The Journal of Clinical Investigation · 2025 · Same journal
• Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy · The Journal of Clinical Investigation · 2021 · Same journal
• Identification of SARS-CoV-2–specific immune alterations in acutely ill patients · The Journal of Clinical Investigation · 2025 · Same journal
• Remodeling glycerophospholipids affects obesity-related insulin signaling in skeletal muscle · The Journal of Clinical Investigation · 2025 · Same journal
• Artificial intelligence for automating the measurement of histologic image biomarkers · The Journal of Clinical Investigation · 2021 · Same journal
• Age-specific effects of vaccine egg adaptation and immune priming on A(H3N2) antibody responses following influenza vaccination · The Journal of Clinical Investigation · 2025 · Same journal
• Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis · The Journal of Clinical Investigation · 2025 · Same journal
• Epilepsy channelopathies go neddy: stabilizing NaV1.1 channels by neddylation · The Journal of Clinical Investigation · 2025 · Same journal
• Genetic therapies for the first molecular disease · The Journal of Clinical Investigation · 2025 · Same journal
• Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma · The Journal of Clinical Investigation · 2025 · Same journal

Metrics

Citations (Crossref)

59