The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

Nature Aging · Published 2026-07-30 · DOI 10.1038/s43587-026-01172-5

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Authors (47)

Aidan R. Cole, Raquel Buj, Apoorva Uboveja, Evan Levasseur, Alexander Tom, Hui Wang, Katarzyna M. Kedziora, Adam Chatoff, Andrea Andress Huacachino, Mariola M. Marcinkiewicz, Amandine Amalric, Baixue Yang, Naveen Kumar Tangudu, Emily Noonan, Jeff Danielson, Miho Naruse, Amal Taher Elhaw, Sierra White, Danyang Li, Callen T. Wallace, Frederick Keeney, Felicia Lazure, Esther Elishaev, Lauren Borho, Hope A. Townsend, Robin D. Dowell, Aaron Clauset, Dorota E. Jazwinska, Matthew S. Laird, Huda Atiya, Denarda Dangaj, Lan G. Coffman, George Tseng, Steffi Oesterreich, Andrew Kossenkov, Qin Liu, Ana P. Gomes, Aditi U. Gurkar, Francisco J. Schopfer, Francesmary Modugno, Simon C. Watkins, Ioannis K. Zervantonakis, Benjamin G. Bitler, Wayne Stallaert, Nadine Hempel, Nathaniel W. Snyder, Katherine M. Aird

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Publication details

Year
2026

Citation

Cole, A., Buj, R., Uboveja, A., et al. (2026). The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming. Nature Aging. https://doi.org/10.1038/s43587-026-01172-5

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