Validated UPLC-MS/MS quantification and intracellular PK-PD Modeling of periplocin-related cardiac glycosides in H/R-injured H9c2 cells

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · Published 2026-07-29 · DOI 10.1016/j.jchromb.2026.125227

Authors (8)

Peng Zhao, Fanjiao Zuo, Caixia Li, Yanjin Li, Haoran Wu, Yingjing Zhao, Yameng Zhu, Jun He

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Zhao, P., Zuo, F., Li, C., et al. (2026). Validated UPLC-MS/MS quantification and intracellular PK-PD Modeling of periplocin-related cardiac glycosides in H/R-injured H9c2 cells. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. https://doi.org/10.1016/j.jchromb.2026.125227

Related articles

• A systematic profiling of chemicalome and metabolome of Citrus aurantium ‘Changshan-huyou’ flavonoids to provide insights into its potential in vivo pharmacodynamic material basis · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Chromatographic Insights into Marine Science: Celebrating 125 Years of the Institute of Marine Research in Norway · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Characterizing the molecular signature of obesity through urine metabolomics in a large Chinese population · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• HPLC-MS/MS quantification of genomic deoxyuridine via differential protonation · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Chemometric-based analytical standardization of bee venom: Resolving the melittin-equivalence paradox through multivariate quality assurance · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Characterization of lipophilic oil fraction from Primula vulgaris: Chemical profile, antioxidant capacity, and DNA damage assessment · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Development and validation of a liquid chromatography-tandem mass spectrometry method for the quantification of twenty-five steroids in equine serum · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Quantifying the aromatic amino acid metabolome: UPLC-MS/MS analysis of aromatic amino acids and their host and co-metabolites in plasma · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Selective monitoring of trace-level catechin and myricetin in herbal and aqueous matrices using magnetic MIP–DSPME: Optimization via design of experiments · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal
• Enzyme inhibition and antioxidant properties of different Melissa officinalis L. extracts: experimental, DFT, molecular docking and molecular dynamics based analyses · Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences · 2026 · Same journal