Circulating thymidine kinase activity predicts survival and optimal treatment sequencing in BRAF-mutated metastatic melanoma in the SECOMBIT trial

Clinical Cancer Research · Published 2026-08-04 · DOI 10.1158/1078-0432.ccr-26-1402

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Authors (27)

Hildur Helgadottir, Mariaelena Capone, Laura Ridolfi, Alberto Zambelli, Luisa Piccin, Helen Gogas, Marco Tucci, Pietro Quaglino, Michele Del Vecchio, Alessandro Marco Minisini, Francesco Spagnolo, Piotr Rutkowski, Virginia Ferraresi, Ana Arance, Michele Guida, Evaristo Maiello, Céleste Lebbé, Jenny Bulgarelli, Vanna Chiarion Sileni, Miriam Paone, Ignacio Melero, Claudia Trojaniello, Mattias Bergqvist, Reinhard Dummer, Diana Giannarelli, Giuseppe Palmieri, Paolo A. Ascierto

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Publication details

Year

2026

Citation

Helgadottir, H., Capone, M., Ridolfi, L., et al. (2026). Circulating thymidine kinase activity predicts survival and optimal treatment sequencing in BRAF-mutated metastatic melanoma in the SECOMBIT trial. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.ccr-26-1402

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