Understanding Biased Signaling and Small-Molecule Binding for Treatment of Type 2 Diabetes Mellitus and Obesity at the Glucagon-Like Peptide-1 Receptor (GLP-1R) Based on Molecular Dynamics Simulations

Medicinal Chemistry Research · Published 2026-07-27 · DOI 10.1007/s00044-026-03579-6

Authors (5)

Jack Brubaker, Soo-Kyung Kim, Bo Li, Moon Young Yang, William A. Goddard

Abstract

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Publication details

Year

2026

Citation

Brubaker, J., Kim, S., Li, B., et al. (2026). Understanding Biased Signaling and Small-Molecule Binding for Treatment of Type 2 Diabetes Mellitus and Obesity at the Glucagon-Like Peptide-1 Receptor (GLP-1R) Based on Molecular Dynamics Simulations. Medicinal Chemistry Research. https://doi.org/10.1007/s00044-026-03579-6

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