suPAR, a Circulating Kidney Disease Factor

Frontiers in Medicine · Published 2021-10-06 · Journal article · DOI 10.3389/fmed.2021.745838 · Cited by 15 (Crossref)

Authors (4)

Changli Wei, Ryan Spear, Eunsil Hahm, Jochen Reiser

Abstract

Urokinase plasminogen activator receptor (uPAR) is a multifaceted, GPI-anchored three-domain protein. Release of the receptor results in variable levels of soluble uPAR (suPAR) in the blood circulation. suPAR levels have been linked to many disease states. In this mini-review, we discuss suPAR as a key circulating molecule mediating kidney disease with a particular focus on differently spliced isoforms.

Abstract from DOAJ. Public domain (CC0 1.0).

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Publication details

Volume

8

Year

2021

Citation

Wei, C., Spear, R., Hahm, E., et al. (2021). suPAR, a Circulating Kidney Disease Factor. Frontiers in Medicine. https://doi.org/10.3389/fmed.2021.745838

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Metrics

Citations (Crossref)

15