Protein SUMOylation confers sorafenib resistance in human hepatocellular carcinoma via the induction of PKM2-mediated glycolysis

Drug Resistance Updates · Published 2026-07-16 · DOI 10.1016/j.drup.2026.101451

Authors (16)

Hongchao Yuan, Yuanjun Lu, Zhuofeng Jiang, Yau-Tuen Chan, Junyu Wu, Zixin Feng, Lin Xu, Qiucheng Li, Pengde Lu, Chun-Fung Kwok, Tung-Leong Fong, Qinguo Huang, Liuya Wei, Yibin Feng, Zhe-Sheng Chen, Ning Wang

Abstract

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Publication details

Year

2026

Citation

Yuan, H., Lu, Y., Jiang, Z., et al. (2026). Protein SUMOylation confers sorafenib resistance in human hepatocellular carcinoma via the induction of PKM2-mediated glycolysis. Drug Resistance Updates. https://doi.org/10.1016/j.drup.2026.101451

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