Sodium butyrate upregulates URAT1-mediated urate reabsorption in HK2 cells by activating FFAR2/p38 MAPK/ELK1/ARRB2 axis and relieving NF-κB–HNF1β competitive binding

Biochemical Pharmacology · Published 2026-08-01 · DOI 10.1016/j.bcp.2026.118308

Authors (10)

Cheng Cao, Mubin Sun, Jiabao Li, Zhenyu Yuan, Yuwei Gu, Yufan Shao, Lisheng Wang, Xiaohua Jin, Yijie Cheng, Bo Fan

Abstract

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Publication details

Year

2026

Citation

Cao, C., Sun, M., Li, J., et al. (2026). Sodium butyrate upregulates URAT1-mediated urate reabsorption in HK2 cells by activating FFAR2/p38 MAPK/ELK1/ARRB2 axis and relieving NF-κB–HNF1β competitive binding. Biochemical Pharmacology. https://doi.org/10.1016/j.bcp.2026.118308

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