Metabolic Dysfunction-Associated Steatotic Liver Disease, Recent Revision of Terminology and Its Implications

The Korean Journal of Gastroenterology · Published 2025-04-25 · DOI 10.4166/kjg.2025.027

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Abstract

A recent major change has occurred in the nomenclature of nonalcoholic fatty liver disease (NAFLD). From the multi-society Delphi consensus statement proposed a new term: metabolic dysfunction-associated steatotic liver disease (MASLD) in 2023. The term "nonalcoholic" was regarded as misleading on multiple grounds. Firstly, it failed to reflect the disease's metabolic origins. Secondly, it hindered patients’ understanding. Thirdly, the terms "nonalcoholic" and "fatty" were regarded as stigmatising by patients and physicians in the field. The proposal of MASLD was a response to these concerns. Since its introduction, the Korean Association for the Study of the Liver has also introduced the new Korean term for MASLD, previously the NAFLD. This article will briefly introduce the new MASLD diagnostic criteria and discuss their implications.

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Publication details

Year
2025

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