American Journal of Ophthalmology Case Reports · Published 2026-08-03 · DOI 10.1016/j.ajoc.2026.102638
Daisuke Nakata, Motohiro Kamei, Taisei Ishio, Kyoko Futamura, Akiko Yagami, Yasuki Ito, Atsuhiro Tanikawa
Purpose: To report our experience with two cases of acrylate allergy confirmed by patch testing, wherein acrylic intraocular lens (IOL) implantation was performed and followed up for 1 year. Observations: A 78-year-old woman with an allergy to acrylic resin consulted a general allergist because of suspected depigmented contact dermatitis. A patch test was positive for methyl methacrylate and 2-hydroxyethyl methacrylate (2-HEMA), which are acrylic resins. Before cataract surgery, patch tests for the IOL and other acrylic resin materials were performed, all of which tested negative. Case 2: A 49-year-old woman was allergic to several substances, including acrylic resin. A patch test was positive for 2-HEMA and ethylene glycol dimethacrylate. We consulted an anesthesiologist regarding immediate-type allergy and explained to the patient about the possibility of IOL removal for delayed-type allergy. Intra-or postoperative complications were not observed in either patient. Postoperative inflammation was similar to that observed after conventional cataract surgeries. During the 1-year follow-up period, worsening of inflammation in the anterior chamber or other symptoms indicative of delayed hypersensitivity were not observed. Conclusions and importance: In two patients with cutaneous acrylate allergy, hydrophobic acrylic IOL implantation was uneventful through the 1-year follow-up period. Careful preoperative patch testing, allergist collaboration, informed consent about uncertain long-term risk, and close follow-up are advised.
Abstract from DOAJ. Public domain (CC0 1.0).
Read the article at the publisher →
Nakata, D., Kamei, M., Ishio, T., et al. (2026). Acrylic intraocular lenses in patients with patch test-confirmed acrylate allergy: two cases with 1-year follow-up. American Journal of Ophthalmology Case Reports. https://doi.org/10.1016/j.ajoc.2026.102638