Clinical implementation of polygenic risk scores—updates on ancestry-adjusted PRS and their use in practice

European Journal of Human Genetics · Published 2026-07-31 · DOI 10.1038/s41431-026-02202-x

Free full text

Authors (3)

Eleanor Roberts, Nicola Flaum, D. Gareth Evans

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Citation

Roberts, E., Flaum, N., Evans, D. (2026). Clinical implementation of polygenic risk scores—updates on ancestry-adjusted PRS and their use in practice. European Journal of Human Genetics. https://doi.org/10.1038/s41431-026-02202-x

Related articles

• Copy number variant analysis by exome sequencing is an effective approach to optimize diagnostic yield for developmental disorders—the DDD-Africa study · European Journal of Human Genetics · 2026 · Same journal
• The co-design, development, and preliminary evaluation of a comprehensive breast cancer risk report incorporating polygenic risk information · European Journal of Human Genetics · 2026 · Same journal
• A thick opt-out for genomic newborn screening, retention, and reuse of genomic data · European Journal of Human Genetics · 2026 · Same journal
• When truncation is not loss of function: neo-tail architecture as a determinant of pathogenicity in NMD-escaping frameshift variants · European Journal of Human Genetics · 2026 · Same journal
• PALM3 and hearing loss: a potential dual diagnosis interfering with novel gene discovery · European Journal of Human Genetics · 2026 · Same journal
• A changed landscape: five-year retrospective on the paradigm shift in genetic testing practices for ALS in Canada · European Journal of Human Genetics · 2026 · Same journal
• Decoding splicing variants in high-throughput sequencing: a functional validation approach integrating deep learning tools · European Journal of Human Genetics · 2026 · Same journal
• Integrative and systematic genomic approaches to improve diagnosis in rare and undiagnosed diseases: results from the RareBoost project · European Journal of Human Genetics · 2026 · Same journal
• Tissue-specific enhanceropathy in Nail-patella syndrome: implications for surveillance and epigenetic diagnostics · European Journal of Human Genetics · 2026 · Same journal
• Family-oriented support in genetic counselling: a scoping review of clinical practice and psychotherapeutic interventions · European Journal of Human Genetics · 2026 · Same journal