Vestnik Dermatologii i Venerologii · Published 2026-07-21 · DOI 10.25208/vdv16997
Yulia A. Gallyamova, Tatyana S. Rusina, Ekaterina S. Dudina
BACKGROUND: Androgenetic alopecia is a widespread disorder that presents therapeutic challenges due to patients' inflated expectations, low treatment adherence associated with inconvenient topical application, and concerns regarding adverse effects. Therefore, exploring new non-invasive approaches to managing hair loss and stimulating hair growth has become particularly relevant. AIM: To evaluate the efficacy and tolerability of the needle-free JetPeel hydro-dermabrasion technology combined with a serum containing DHQG (dihydroquercetin-glucoside), glycine, zinc chloride, EGCG (epigallocatechin-gallate-glucoside), acetyl tetrapeptide-3, and biochanin A (from red clover extract) in women with androgenetic alopecia in a real-world clinical setting. METHODS: A prospective, uncontrolled, pragmatic study was conducted, blinded to the trichogram assessor. It enrolled 22 women with Ludwig stage I–III androgenetic alopecia. The patients received JetPeel procedures with serum once weekly for 5 weeks, along with daily home application of the serum. The analyzed trichoscopic parameters included the proportion of terminal/vellus hairs, single/double/triple follicular units, hair diameter. Subjective satisfaction and comfort were assessed using a 5-point Likert scale and a Visual Analogue Scale, respectively. RESULTS: After 5 weeks, a statistically significant reduction in the proportion of single follicular units by 20% (p = 0.001) and an increase in the proportion of double units by 11.8% (p = 0.003) were observed. Median satisfaction was 4.5 points (86.4% of patients rated the outcome as 4 or 5). Comfort according to Visual Analogue Scale was 8.9 ± 1.2 out of 10. No serious adverse events were reported. CONCLUSION: The JetPeel technology with complex serum demonstrates early positive trichoscopic changes, high subjective satisfaction, and a favorable safety profile, supporting its recommendation as an additional treatment option for androgenetic alopecia in women.
Abstract from DOAJ. Public domain (CC0 1.0).
Read the article at the publisher →
Gallyamova, Y., Rusina, T., Dudina, E. (2026). EFFICACY OF THERAPY FOR ANDROGENIC ALOPECIA IN WOMEN USING HYDRODERMABRASION AND NEEDLE-FREE INFUSION: A PROSPECTIVE STUDY. Vestnik Dermatologii i Venerologii. https://doi.org/10.25208/vdv16997