Frontiers in Oral Health · Published 2026-08-03 · DOI 10.3389/froh.2026.1900518
Jonathan Andrés Panchi-Lasluisa, Virgen María Acuña-Peña, Sebastián Álvarez-Razo, Juan Marcos Parise-Vasco
Schwannoma is a benign, encapsulated, slow-growing tumor that arises from Schwann cells. Approximately 25%–45% of extracranial schwannomas occur in the head and neck region, accounting for 1%–8% of all neoplasms. However, involvement of the infraorbital nerve is exceptionally rare. This report describes the surgical management of an infraorbital nerve schwannoma using a transconjunctival approach with lateral canthotomy, and documents the clinical, functional and aesthetic outcomes at 12 months. A 32-year-old woman with a history of hypochromic microcytic anemia presented with a progressively enlarging mass in the right infraorbital region that had been present for four years, associated with mild paresthesia in the nasolabial region. The main reason for consultation was aesthetic concern due to facial protrusion. Physical examination revealed a firm, painless subcutaneous mass without local inflammatory signs. Contrast-enhanced computed tomography revealed a solid, lobulated lesion measuring approximately 60 mm in maximum diameter in the right infraorbital region. Imaging features suggested an origin from the infraorbital foramen and involvement of the corresponding nerve; there was no evidence of osteolysis. Fine-needle aspiration cytology (FNAC) suggested a mesenchymal neoplasm. Surgical excision was performed under general anesthesia via a transconjunctival approach with lateral canthotomy. The infraorbital nerve was identified and preserved intraoperatively. Histopathological examination confirmed a schwannoma, showing spindle-shaped cells with Verocay bodies. The patient had a favorable clinical course. At the 12-month follow-up, facial symmetry and preserved sensory function were confirmed, as was the absence of recurrence.
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Panchi-Lasluisa, J., Acuña-Peña, V., Álvarez-Razo, S., et al. (2026). Surgical excision of an infraorbital nerve schwannoma via a transconjunctival approach with lateral canthotomy: a case report. Frontiers in Oral Health. https://doi.org/10.3389/froh.2026.1900518