Journal of Clinical and Translational Endocrinology Case Reports · Published 2026-01-30 · DOI 10.1016/j.jecr.2026.100210
Introduction: A collision tumor is a rare occurrence in which two distinct tumor types coexist within an organ while maintaining distinct borders. Case: A 61-year-old female referred to our clinic for the evaluation of a thyroid mass. Ultrasound revealed a large, solid, isoechoic nodule in the right lobe measuring 4.5 × 3.1 cm (TI-RADS category 3). Fine-needle aspiration biopsy was suspicious for a follicular neoplasm, Hürthle cell (oncocytic) type, Bethesda system class IV. The patient underwent right lobectomy, and the final pathology report revealed minimally invasive follicular carcinoma. Completion thyroidectomy revealed papillary carcinoma of the left lobe. Conclusion: Managing thyroid collision tumors is challenging due to the presence of two distinct tumors with different biological aggressiveness, treatment options, and prognoses. Addressing how these factors influence treatment planning can enhance understanding of patient management and outcomes.
Abstract from DOAJ. Public domain (CC0 1.0).
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