Health Sciences Review · Published 2024-09-04 · DOI 10.1016/j.hsr.2024.100197
This exhaustive review examines the therapeutic possibilities of butein, an organic compound sourced from plants, which has a long history in traditional medicine. Initiating with an investigation of plant-based remedies in native societies, the review emphasizes the importance of researching the physiological effects of plant-derived chemicals. The multifaceted biological activities of butein, encompassing its anti-inflammatory, antioxidant, anti-cancer, and neuroprotective properties are systematically analyzed. Detailed discussions elucidate the underlying mechanisms driving these activities and the wide-ranging applications of butein in managing various illnesses such as cancer, neurodegenerative disorders, and cardiovascular ailments. The article also explores the challenges associated with developing butein as a therapeutic agent, including issues with bioavailability and toxicity. The authors deliberate on diverse approaches to surmount these obstacles, incorporating the application of innovative drug delivery systems and the synthesis of artificial analogs. On the whole, this review offers a thorough outline of the therapeutic potential of butein and underscores the significance of investigating plant-based compounds for the formulation of novel medications. It is deduced that butein holds substantial promise as a therapeutic remedy, necessitating further exploration to fully comprehend its mechanisms of operation and potential applications in clinical environments.
Abstract from DOAJ. Public domain (CC0 1.0).
Read the article at the publisher →