Dual TYK2/JAK1 Inhibition by Brepocitinib Suppresses TNF-α–Driven Oxidative Stress, PI3K/AKT/mTOR Activation and FAK-Dependent Migration in Rheumatoid Arthritis Synoviocytes

ACTA POLONIAE PHARMACEUTICA · Published 2026-03-03 · DOI 10.32383/appdr/217369

Free full text

Authors being retrieved — see the publisher record. https://doi.org/10.32383/appdr/217369

Abstract

PubPorta does not have an abstract for this article yet.

Read the article at the publisher →

Publication details

Year

2026

Related articles

• Sales of Bone-Strengthening Preparations Used in Osteoporosis Prevention: Analysis of Pharmacy Sales Data in Poland · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Neuroprotective Effects of Coumarin Derivatives in Human SH-SY5Y Neuronal Cells: Structure–Activity Insights · ACTA POLONIAE PHARMACEUTICA · 2025 · Same journal
• Pharmacotherapy Optimization in Breastfeeding Mothers: A Retrospective Analysis of Interprofessional Pharmacist Interventions Using the MILC-APIC Tool · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Mechanistic Impact of Suppressor of Cytokine Signaling 1 on the Malignant Biological Behaviors of Cervical Cancer Cell Lines · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Synthesis and In Vitro Anti-Lung Cancer Activity of an N-Glucoside Derivative of Thiazole Compound KY-05009 · ACTA POLONIAE PHARMACEUTICA · 2025 · Same journal
• Viral Cardiovascular Injury as a Potential Modifier of Cancer Therapy–Related Cardiotoxicity: A Pharmacovirological Review · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Design, Optimization, and Stability Evaluation of a Self-Nanoemulsifying Drug Delivery System (SNEDDS) to Improve Solubility and Pharmacokinetics of Andrographolide · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Overexpression of miR-137 Protects Rat Spinal Cord Neurons From LPS-Induced Inflammation In Vitro Through Targeting RIP3 and Inhibiting IKKβ/NF-κB Signaling Pathway · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• Computational Prediction of ADMET Properties and Safety Profiles of Trans- and Cis-Cinnamaldehyde · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal
• SIRT1 Attenuates Oxyhemoglobin-Induced Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Neuronal Cells · ACTA POLONIAE PHARMACEUTICA · 2026 · Same journal