Journal of Primary Care and Community Health · Published 2026-04-01 · DOI 10.1177/21501319261438754
Objectives: Suicide remains a significant public health challenge in the United States and globally, with risk influenced not only by mental health conditions but also by social and structural factors. This analysis examines how social determinants of health contribute to suicide risk and identifies evidence-supported nurse practitioner (NP) interventions that may reduce vulnerability in primary care settings. Methods: A theory-based analysis was conducted using the World Health Organization Social Determinants of Health framework, the Stress Process Model, and Joiner’s Interpersonal Theory of Suicide to examine how social conditions influence suicide risk and to identify opportunities for NP intervention. Results: Economic hardship contributes to chronic stress and perceived burdensomeness, social isolation weakens protective belongingness, and limited access to behavioral health services delays treatment of depression and suicidal ideation. Evidence supports NP-led strategies, including social determinants screening, collaborative care models, integrated behavioral health services, and structured suicide risk assessment protocols as practical approaches to addressing these risks. Conclusion: Effective suicide prevention requires expanding beyond symptom management to include upstream social risk factors. Nurse practitioners are well-positioned to lead these efforts through early identification, integrated care delivery, and whole-person primary care models addressing both clinical and social drivers of suicide risk.
Abstract from DOAJ. Public domain (CC0 1.0).
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