Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice

Molecular Neurodegeneration · Published 2026-07-16 · DOI 10.1186/s13024-026-00978-6

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Authors (29)

Hayk Davtyan, Sarah Naguib, Yuliya Voskobiynyk, Jean Paul Chadarevian, Joia K. Capocchi, Jeannie L. Giacchino, Ghazaleh Eskandari-Sedighi, Vivianna DeNittis, Jeremy B. Ford, Ani Agababian, Jasmine Nguyen, Alina L. Chadarevian, Madison S. Sutherland, Sepideh Kiani Shabestari, Kayla Tran, Bret Holt, Alissa L. Nana, Jiasheng Zhang, Salvatore Spina, Man Ying Wong, Lea T. Grinberg, William W. Seeley, Eric Huang, Claire D. Clelland, Shiaoching Gong, Li Fan, Jeanne T. Paz, Mathew Blurton-Jones, Li Gan

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Publication details

Year

2026

Citation

Davtyan, H., Naguib, S., Voskobiynyk, Y., et al. (2026). Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice. Molecular Neurodegeneration. https://doi.org/10.1186/s13024-026-00978-6

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