Prevalence of neurocognitive impairments in adults with chronic pain: A cross-sectional study

South African Journal of Psychiatry · Published 2025-09-25 · DOI 10.4102/sajpsychiatry.v31i0.2500

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Abstract

Background: There is a strong link between chronic pain and neurocognitive impairment. The co-occurrence of the two disorders often leads to a poor quality of life and significant disability. Aim: To determine the prevalence of neurocognitive impairments in adults with chronic pain. Setting: The study was conducted at a tertiary hospital in Pietermaritzburg, KwaZulu-Natal. Methods: This cross-sectional study was conducted at a pain clinic within a tertiary hospital in Pietermaritzburg, KwaZulu-Natal. Participants were required to be clinic attendees, proficient in English, and have a minimum of a Grade 7 education. Exclusion criteria included neurological disorders, significant language barriers, or ineligible age. Recruitment used purposive sampling with informed consent. Data were collected using socio-demographic and clinical questionnaires, namely, the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), and the Physical Self-Maintenance Scale (PSMS). The primary outcome was the prevalence of neurocognitive impairment; secondary outcomes examined associations with demographic and clinical factors using both descriptive and inferential statistics. Results: A total of 105 participants (59 females and 46 males) were enrolled in the study. The mean age of the participants was 55.1 ± 6.75 years. A total of 73.3% (n = 77) of participants screened positive for neurocognitive impairment on MoCA and 55.2% on MMSE. Conclusion: Chronic pain is associated with impairments in neurocognitive performance, particularly in short-term memory and executive functioning. Contribution: A significant correlation was found between lower education levels and neurocognitive impairment (p = 0.02 for MoCA, p = 0.04 for MMSE).

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Publication details

Year
2025

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