BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease

Gastroenterology · Published 2026-06-01 · DOI 10.1053/j.gastro.2026.05.022

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Authors (47)

Qi Li, Ryusuke Nambu, Hu Yaqiang, Xiang Shen, Carmen Argmann, Rei Guan, Erin Janssen, Tom Le Voyer, Neil Warner, Daniel D. Yu, Jing Guo, Kelvin Long, Jodie Ouahed, Michael Field, Lauren Collen, Jonas Bibus, David Illig, Meino Rohlfs, Ziqi Yu, Shaohong Yang, Wenjuan Li, Craig D. Platt, Phillip H. Comella, Daniel Jordan, Mayte Suárez-Fariñas, Mohammed F. Alosaimi, Lauren A. Peters, Jeremie Rosain, Claire Fieschi, Anne Puel, Elena W.Y. Hsieh, Takeo Naito, Zhiyang Zeng, Marta Velasco Rodríguez-Belvís, Laura Palomino, Peter Küster, Dalin Li, Christoph Klein, Scott B. Snapper, Jean-Laurent Casanova, Raif Geha, Edward Hoffenberg, Dermot P.B. McGovern, Eric Schadt, Daniel Kotlarz, Dali Li, Aleixo M. Muise

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Publication details

Year
2026

Citation

Li, Q., Nambu, R., Yaqiang, H., et al. (2026). BIRC3 (Encoding cIAP2) Variants Result in Dysregulated RIPK1 Signaling Leading to Increased Epithelial Cell Death and Are Associated With Monogenic Crohn’s Disease. Gastroenterology. https://doi.org/10.1053/j.gastro.2026.05.022

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