Current Directions in Biomedical Engineering · Published 2025-09-01 · DOI 10.1515/cdbme-2025-0165
The entoptic view of the retina is a fascinating phenomenon that is caused by light stimulation. Over the course of the past two years, we have been developing our Purkinje Retinal Image Stabilizer (PRIS) method to simplify entoptic testing for retinal examinations. Our non-invasive method is intended as a retinal function test and to make disease-related changes in the retina or the retinal blood vessels visible to the user. Technically, we have implemented it in a small light stimulator, the PRIS-Tool. In a next step, clinical studies have to be conducted to verify the reliability and safety of the PRIS method as an ophthalmic screening tool for medical applications. We are focused on its use for the early detection of diabetic retinopathy worldwide and for the preoperative assessment of retinal function in cataract patients in low-income countries. For clinical studies, enhancements and new functions have been implemented in the redesigned PRIS-Tool device to facilitate handling and optimize in-house assembly. We also present our approach for assessing photobiological safety in accordance with IEC/EN 62471.
Abstract from DOAJ. Public domain (CC0 1.0).
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