Modulation of morphine tolerance and dependence by pyrroloquinoline quinone in mice: Insights into mechanistic bridge from N-methyl-D-aspartate receptors-calcium/calmodulin-dependent protein kinase II signaling to oxidative neuroinflammation

Journal of Pharmacology and Experimental Therapeutics · Published 2026-06-04 · DOI 10.1016/j.jpet.2026.104956

Authors (6)

Mariam A. Nicola, Fatma H. Hefny, Rana M.I. Morsy, Fatma M. Abdel-Maksoud, Marwa G. Gamea, Mostafa M. Hamdy

Abstract

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Publication details

Year

2026

Citation

Nicola, M., Hefny, F., Morsy, R., et al. (2026). Modulation of morphine tolerance and dependence by pyrroloquinoline quinone in mice: Insights into mechanistic bridge from N-methyl-D-aspartate receptors-calcium/calmodulin-dependent protein kinase II signaling to oxidative neuroinflammation. Journal of Pharmacology and Experimental Therapeutics. https://doi.org/10.1016/j.jpet.2026.104956

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