Hematology/ Oncology and Stem Cell Therapy · Published 2023-07-20 · DOI 10.56875/2589-0646.1110
Background and objectives: Several strategies and procedures have been described for thawing umbilical cord blood (UCB) products. The ideal method for each center depends on the resources, staff training, and access to each of these. We retrospectively evaluated the incidence of side effects using the bedside thaw method after unrelated UCB transplantation. Patients and methods: For 34 children, patient, donor, graft characteristics, and side effects were identified. In addition, we attempted to identify the risk factors that could be associated with side effects. Results: 68% of patients experienced any adverse reaction. All the reactions were mild and transient events. The most frequent side effects were vomiting, hypertension, hemolytic reactions, and fever. There were more gastrointestinal events with a faster infusion rate. Conclusion: The thawed at the bedside method is a practical, easy, and safe technique for cord blood transplantation in pediatric-patient settings.
Abstract from DOAJ. Public domain (CC0 1.0).
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