Malignant Transformation of Normal Oral Tissue to Dysplasia and Early Oral Squamous Cell Carcinoma: An In Silico Transcriptomics Approach

Analytical Cellular Pathology · Published 2024-01-01 · DOI 10.1155/2024/6260651

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Abstract

Conclusion: This study identified vital genes, pathways, and prognostic markers involved in the malignant transformation from normal oral tissue to OPL and primary OSCC, providing insights for early diagnosis and targeted therapy development. Cross-validation with an independent RNA-seq dataset and immunohistochemistry reinforced the findings, supporting the robustness of the identified molecular signatures.

Abstract from DOAJ. Public domain (CC0 1.0).

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Publication details

Year
2024

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