Role of CYP3A5 and CYP3A4 in the metabolism and toxicity of 10-hydroxyl mesaconitine, a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), in vitro and in vivo

DRUG METABOLISM AND DISPOSITION · Published 2026-06-29 · DOI 10.1016/j.dmd.2026.100352

Authors (10)

Yu Fu, Yu Cai, Fangyuan Li, Tongyang Ma, Caiyan Wang, Rong Zhang, Zhongqiu Liu, Dongyan Bai, Qi Liang, Lijun Zhu

Abstract

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Publication details

Year

2026

Citation

Fu, Y., Cai, Y., Li, F., et al. (2026). Role of CYP3A5 and CYP3A4 in the metabolism and toxicity of 10-hydroxyl mesaconitine, a new potential toxicity marker of Radix Aconiti Lateralis Preparata (Fuzi), in vitro and in vivo. DRUG METABOLISM AND DISPOSITION. https://doi.org/10.1016/j.dmd.2026.100352

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