Current Issues in Pharmacy and Medical Sciences · Published 2025-08-12 · DOI 10.12923/cipms-2025-0022
Maxillary sinus carcinoma (MSC) is a rare malignancy characterized by diagnostic and therapeutic complexity, often presenting late in its clinical course. This report details a unique and aggressive case of MSC in a 57-year-old male. Despite prompt multimodal treatment, including surgery, radiochemotherapy (RCTH) and sequential lines of palliative chemotherapy (CTH), the disease demonstrated rapid progression and resistance to standard therapies. Management was guided by a patient-centered approach, emphasizing shared decision-making in light of the patient’s clinical trajectory and quality-of-life considerations. This case highlights the challenges of treating aggressive MSC and underscores the necessity for individualized care strategies in managing rare and refractory head and neck cancers.
Abstract from DOAJ. Public domain (CC0 1.0).
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