Journal of Clinical Hypertension · Published 2026-07-01 · DOI 10.1111/jch.70317
Pujuan Liu, Shang Wang, Huili Liu, Jing Wang, Man Zhang, Hong Shen, Sha Liu, Beibei Xing
ABSTRACT This prospective observational study investigated whether systolic blood pressure variability (SBPV) during the transitional care period predicts long‐term outcomes after coronary artery bypass grafting (CABG). We enrolled 120 consecutive patients undergoing isolated CABG between 2020 and 2024 in a structured Transitional Care Service System. Office blood pressure was measured at scheduled visits. SBPV was quantified using the coefficient of variation (CV), and patients were stratified by median SBP‐CV (8.4%) into low‐ and high‐variability groups. The primary endpoint was major adverse cardiac and cerebrovascular events (MACCE). During a median follow‐up of 46 months (corresponding to 34 months post‐landmark), 19 MACCE events occurred in the landmark cohort of 116 patients (4 early events were excluded). The high‐variability group experienced significantly more events than the low‐variability group (26.3% vs. 6.8%, p = 0.005), with markedly reduced event‐free survival (log‐rank p = 0.005). After multivariable adjustment for age, diabetes mellitus, number of measurements, and mean systolic blood pressure, high SBPV remained an independent predictor of MACCE (hazard ratio 2.85, 95% confidence interval 1.12–7.24, p = 0.028). Sensitivity analyses using alternative metrics confirmed these findings, whereas mean systolic blood pressure was not predictive. In conclusion, high visit‐to‐visit SBPV during postoperative transitional care independently predicts long‐term cardiovascular events after CABG. Monitoring blood pressure stability may enhance risk stratification in this high‐risk population.
Abstract from DOAJ. Public domain (CC0 1.0).
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Liu, P., Wang, S., Liu, H., et al. (2026). Visit‐to‐Visit Systolic Blood Pressure Variability Predicts Long‐Term Cardiovascular Events After Coronary Artery Bypass Grafting. Journal of Clinical Hypertension. https://doi.org/10.1111/jch.70317