The Lancet Regional Health. Western Pacific · Published 2026-07-01 · DOI 10.1016/j.lanwpc.2026.101919
Shudan Liu, Di Wu, Siyan Ye, Yuqing Xiao, Meng Wu, Shu Chen, Xinyu Zhang, Lei Guo, Qin Zhang, Yang Zhou, Xiangju Wu, Qian Yang, Rongchang Xiao, Jie Zhang, Xinyi Feng, Jinghan Wang, Xianwen Shi, Xiaoyuan Zhang, Jiawei Xu, Jianchao Shao, Shenglan Tang, Qin Liu
Summary: This scoping review mapped adolescent HPV vaccination policies across 84 low- and middle-income countries (LMICs) with national HPV immunization programs and synthesized implementation evidence through July 2025. Focusing on adolescents aged 9–14 years, we identified policy convergence in target age, school-based delivery, and free vaccination provision, alongside divergence in gender eligibility, vaccine type, and funding mechanisms across income levels. Nearly half of LMICs have adopted single-dose schedules, reflecting a clear trend toward dosing simplification. Despite these policy advances, only 9.8% of countries achieved the WHO 90% complete vaccination target among females by age 15. Coverage analysis suggested that school-based programs maintained more stable performance over time than health facility-based approaches. Implementation evidence identified four facilitating factors, while barriers varied by income level. School-based programs complemented by mixed delivery approaches and single-dose schedules may offer a promising pathway toward the 2030 cervical cancer elimination goals.
Abstract from DOAJ. Public domain (CC0 1.0).
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Liu, S., Wu, D., Ye, S., et al. (2026). HPV vaccination policies and implementation for adolescents in low- and middle-income countries: a scoping review. The Lancet Regional Health. Western Pacific. https://doi.org/10.1016/j.lanwpc.2026.101919