Dental Hypotheses · Published 2025-01-01 · DOI 10.4103/denthyp.denthyp_77_23
Introduction: We aimed to investigate the salivary cytomegalovirus (CMV) and Epstein–Barr virus (EBV) antibody levels among patients with recurrent aphthous stomatitis (RAS). Methods: Eighty subjects were participated in this study: 40 patients with RAS and 40 healthy persons. A saliva sample was taken from each group for evaluation of salivary levels of CMV and EBV IgG by using a sandwich enzyme-linked immune-sorbent assay. Results: Salivary levels of CMV (P = 0.072, mean difference: −0.174, 95% confidence interval: −0.364 to 0.0161) and EBV (P = 0.004, mean difference: −0.291, 95% confidence interval: −0.488 to −0.0943) IgG among patients with RAS were significantly higher than healthy subjects. Conclusion: This study emphasizes that CMV and EBV infections may associated with the etiology of RAS.
Abstract from DOAJ. Public domain (CC0 1.0).
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