Healthcare in Low-resource Settings · Published 2026-01-07 · DOI 10.4081/hls.2026.14132
Infective Endocarditis (IE) is a rare but potentially lethal infection of the endocardium and heart valves, native or prosthetic. Staphylococcus aureus-associated IE was identified as the most common cause of IE and is an independent predictor of mortality. Most cases of IE are left-sided and involve a single valve. Here we report a case of Staphylococcus aureus bivalvular endocarditis (MVE) in a patient with a history of intravenous drug use and provide a literature review of MVE identification, treatment, and prognosis. Our patient underwent a 4-week course of intravenous antibiotic therapy for infective endocarditis. Serial Transthoracic Echocardiography (TTE) during hospitalization demonstrated a reduction in the size of the vegetations on both the mitral and tricuspid valves. Upon clinical stabilization, the patient was transitioned to oral antibiotic therapy for an additional two weeks. At discharge, the patient was in stable condition and was advised to continue outpatient follow-up. Routine surveillance with TTE every three months was recommended to monitor for recurrence or progression.
Abstract from DOAJ. Public domain (CC0 1.0).
Read the article at the publisher →