Lessons from the COVID-19 Pandemic Era: Vulnerabilities, Interventions, and Vaccination Strategies in Kidney Replacement Therapy Populations

Kidney Diseases · Published 2025-09-02 · DOI 10.1159/000548215

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Abstract

<p>Background: Although the World Health Organization no longer classifies coronavirus disease 2019 (COVID-19) as a global health emergency, its long-term sequelae continue to affect survivors physically, psychologically, and socially. Summary: This review focuses on a vulnerable population – patients receiving kidney replacement therapy (KRT) – and summarizes their COVID-19-associated epidemiological characteristics, clinical manifestations, clinical outcomes, interventions, and vaccination challenges. Key Messages: KRT patients faced markedly higher severe acute respiratory syndrome coronavirus 2 infection risks, atypical clinical presentations, and high mortality rates. Specialized management strategies for patients on KRT were recommended. COVID-19 vaccination formed the cornerstone of controlling COVID-19 but also raised concerns over its long-term safety and immunogenicity profiles. </p>

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Publication details

Year
2025

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