Journal of Investigative Medicine High Impact Case Reports · Published 2026-03-01 · DOI 10.1177/23247096261435524
Neuroendocrine tumors (NETs) represent neoplastic growths that arise from cells of neuroendocrine differentiation. They constitute a clinical spectrum from low-grade NETs with an indolent course to the aggressive undifferentiated high-grade neuroendocrine carcinoma. We report a rare case of axillary neuroendocrine carcinoma of unknown primary site. The patient underwent axillary nodal excision followed by radiation therapy with good tolerability. However, distant cerebellar metastatic recurrence was evident 9 months later. We additionally review the literature on cases of axillary NETs. Their heterogenous behavior depict the need for strict clinical surveillance to allow for early identification of occult secondary metastasis and improve prognostic outcomes.
Abstract from DOAJ. Public domain (CC0 1.0).
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