TGF-β1 drives neutrophil extracellular traps formation to promote CD8 + T cell exhaustion via the ERK-c-Fos-JunB axis, mediating gastric cancer immunotherapy resistance

Journal for ImmunoTherapy of Cancer · Published 2026-08-01 · DOI 10.1136/jitc-2026-015618

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Authors (10)

Ziting Qu, Zhikun Wang, Yongtao Hu, Xiaoli Wei, Wenxi Ding, Sachiyo Nomura, Xiaoyu Guo, Hui Feng, Yiyin Zhang, Kangsheng Gu

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Year
2026

Citation

Qu, Z., Wang, Z., Hu, Y., et al. (2026). TGF-β1 drives neutrophil extracellular traps formation to promote CD8 + T cell exhaustion via the ERK-c-Fos-JunB axis, mediating gastric cancer immunotherapy resistance. Journal for ImmunoTherapy of Cancer. https://doi.org/10.1136/jitc-2026-015618

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